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Multiscale Entropy Analysis of Retinal Signals Reveals Reduced Complexity in a Mouse Model of Alzheimer's Disease

Alzheimer’s disease (AD) is one of the most significant health challenges of our time, affecting a growing number of the elderly population. In recent years, the retina has received increased attention as a candidate for AD biomarkers since it …

Machine Learning Models and Statistical Complexity to Analyze the Effects of Posture on Cerebral Hemodynamics

The mechanism of cerebral blood flow autoregulation can be of great importance in diagnosing and controlling a diversity of cerebrovascular pathologies such as vascular dementia, brain injury, and neurodegenerative diseases. To assess it, there are …

Using complexity-entropy planes to detect Parkinson's disease from short segments of haemodynamic signals

Objective: There is emerging evidence that analysing the entropy and complexity of biomedical signals can detect underlying changes in physiology which may be reflective of disease pathology. This approach can be used even when only short recordings …

Retinal Ganglion Cells Functional Changes in a Mouse Model of Alzheimer's Disease Are Linked with Neurotransmitter Alterations

Background: Alzheimer's disease (AD) is the most prevalent form of dementia worldwide. This neurodegenerative syndrome affects cognition, memory, behavior, and the visual system, particularly the retina. Objective: This work aims to determine whether …

Analysis of cerebral blood flow entropy when listening music with emotional content

Music is one of the most sublime stimulus that human beings can experience. Despite being just an acoustic wave that exert little physical action on a subject, it triggers profound changes in emotions and physiological states. This study explores the …

Assessment of dynamic cerebral autoregulation in humans: Is reproducibility dependent on blood pressure variability?

We tested the influence of blood pressure variability on the reproducibility of dynamic cerebral autoregulation (DCA) estimates. Data were analyzed from the 2nd CARNet bootstrap initiative, where mean arterial blood pressure (MABP), cerebral blood …

Copper price prediction using support vector regression technique

Predicting copper price is essential for making decisions that can affect companies and governments dependent on the copper mining industry. Copper prices follow a time series that is nonlinear and non-stationary, and that has periods that change as …

d-serine regulation of the timing and architecture of the inspiratory burst in neonatal mice

d-serine, released from mouse medullary astrocytes in response to increased CO2 levels, boosts the respiratory frequency to adapt breathing to physiological demands. We analyzed in mouse neonates, the influence of d-serine upon inspiratory/expiratory …

Recognition of Nausea Patterns by Multichannel Electrogastrography

Nausea is a common set of symptoms related to several underlying physiological causes, usually difficult to identify a priori. Detecting nausea before emesis (vomiting) is particularly important for patients who are still unconscious after surgery, …

Creating a neuroprosthesis for active tactile exploration of textures

Intracortical microstimulation (ICMS) of the primary somatosensory cortex (S1) can produce percepts that mimic somatic sensation and, thus, has potential as an approach to sensorize prosthetic limbs. However, it is not known whether ICMS could …